There are many couples who divert their minds to get in the procedure of IVF
known as in vitro fertilization who are unable to get pregnant after trying
number of times.
FISH stands for fluorescent in situ hybridization. This technology is a part of
pgd. In this technology DNA probes are used which have been treated with a
florescent dye, so that each chromosome tested gets lighted with different type
of colors. Colored dots are then counted with the help of a microscope. The use
of few probes at a time is the major drawback of this technology. This results
in examination of only 9 to 12 of the total chromosomes. Accuracy of FISH
technology is around 90% for the chromosomes which are tested. But in this pgd
technology some chromosomes remain untested which creates problem which leads to
transfer of aneuploidy with one of the untested chromosomes.
CGH Technology is also a type of pgd. It is known as Comparative Genomic
Hybridization. This technology screens all the 24 chromosomes. To determine the
imbalances CGH uses the control DNA and fluorescent dyes. Standard CGH, array
CGH are the types of CGH. CGH process takes longer time because all embryos are
first screened to be frozen and then transferred during a later period of the
menstrual cycle. Results of CGH can get delivered on time.
There are various situations when couples get benefited from the IVF along with
parental support. Some of such situations are:
• Women whose age is over 35 can get help from the IVF to get rid of the
problem.
• Many couples experiences a multiple case of miscarriages, they also fall in
the same category.
• A couple who had fetus or is the child was diagnosed with abnormal chromosome.
Though pgd has helped many couples in getting child but it has few limitations
also. It is not such that pgd method is right for everyone. All the couples have
different types of problem; it depends on their problem what technology will be
used for treating them. You should know that no test guarantees the birth of a
healthy baby. The fact should always be remembered that pgd cannot out rule the
mosaicism. This occurs when the single cell of the embryo differ chromosomally
from the other cells that are present in the embryo.
If you are in need of any such procedure to get a child, then it becomes your
responsibility to ensure that you are undertaking the right decision. For this
you should make enough and detailed enquires with your doctor so that you may
come to know what you require. This is a very crucial decision so you should try
to be careful.
